巴西妇女患有第一阶段和第三阶段非转移性乳腺癌的症状集群:一个横截面研究
Luís Carlos Lopes-Júnior1,2, Etreo Junior Carneiro da Silva Minarini1, Raphael Manhães Pessanha1
1Health Sciences Center, Graduate Program in Public Health (PPGSC/UFES) at the Federal University of Espirito Santo, Vitória, Espírito Santo, Brazil.
The breast journal
|March 4, 2026
概括
乳腺癌的症状集群根据阶段不同. 第一个阶段的患者经历了更多的认知和情绪症状,而第三阶段的患者有更多的疼痛和疲劳,告知个性化护理.
科学领域:
- 在瘤学瘤学.
- 症状科学 症状科学
- 生活质量研究 研究 生命质量研究
背景情况:
- 乳腺癌是全球女性的主要恶性瘤,需要有效的症状管理以及治疗进展.
- 症状集群,而不是孤立的症状,显著影响患者的福祉和生活质量.
- 了解特定阶段的症状模式对于制定个性化的支持性护理策略至关重要.
研究的目的:
- 识别和比较女性的症状集群的第一阶段和第三阶段非转移性乳腺癌.
- 分析这些症状集群的患病率,强度和不适.
- 根据疾病阶段,为量身定制的支持性护理干预提供信息.
主要方法:
- 一项涉及87名正在接受治疗的I-III期乳腺癌妇女的横截面研究.
- 使用纪念症状评估尺度 (MSAS) 进行症状评估.
- 统计分析,包括针对流行率的引导重新抽样以及针对症状集群的层次/k-means集群.
主要成果:
- 第一个阶段的患者经常报告疼痛,担忧,睡眠困难和疲劳.
- 第三阶段患者最常经历疼痛,疲劳,担忧和口腔干燥.
- 与第三阶段相比,I阶段的患者表现出更高的集中力困难,呼吸短促,悲伤和脱发的患病率.
- 每个阶段都确定了不同的症状集群:第一阶段 (神经心理,胃肠道,神经认知,心理) 和第三阶段 (精神神经认知,胃肠道,化疗相关,神经认知).
结论:
- 非转移性乳腺癌的症状经历是异质的,并且根据疾病阶段有很大差异.
- 在不同阶段出现不同的症状集群概况,突出显示需要特定阶段的支持性护理.
- 根据特定阶段的症状模式,个性化和有针对性的支持性护理策略可以改善生活质量和临床结果.
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