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Updated: May 1, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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按键组装的性树突的合理设计:研究抗癌活性和分子动力学研究

Tamer El Malah1, Ahmed A El-Rashedy2,3

  • 1Photochemistry Department, Chemical Industries Research Institute, National Research Centre 33 El Buhouth Street, P.O. Box 12622 Cairo Egypt tmara_nrc3000@yahoo.com.

RSC advances
|March 4, 2026
PubMed
概括

通过点击化学合成的状树枝体显示出强大的抗癌活性. 完全性树枝状体 (9) 显示出高选择性和降低毒性,为向癌症治疗提供了有希望的头.

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Structure-Activity Relationships and Drug Design01:28

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Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
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