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磁性可回收的核心外Ag@Fe₃O₄纳米颗粒用于水传播病原体无活化和医疗生物膜消除

Jun Ge¹, Xuechao Shi¹, Shuxian Hou¹

¹School of Biological and Food Engineering, Anhui Polytechnic University, Wuhu, Anhui Province 241000, China.

ACS applied bio materials

|March 4, 2026

概括

核心外的铁氧化银纳米颗粒 (Ag@Fe3O4 NPs) 有效地消除了耐药细菌和生物膜. 这些超偏磁纳米粒子为水处理和医疗器械消毒提供了可持续的解决方案.

科学领域:

纳米技术纳米技术
材料科学材料科学材料科学
环境科学环境科学

背景情况:

水中的耐药细菌对公众健康构成重大风险.
废水和医疗器械是致病性细菌生长和生物膜形成的热点.
新型抗菌剂对于有效消除病原体至关重要.

研究的目的:

为了合成和表征核心外Ag@Fe3O4NP用于抗菌应用.
为了研究Ag@Fe3O4NP的协同抗菌机制.
评估Ag@Fe3O4NP在水处理和生物薄膜去除方面的有效性.

主要方法:

的Ag@Fe3O4NP的溶热合成.
描述NP结构,超对磁性和抗菌活性.
对生物膜破坏,核酸泄漏和ROS生成的评估.
水处理模拟和磁回收周期.
在体外测试医疗导管生物膜.

主要成果:

Ag@Fe3O4 NPs表现出持续的抗菌活性,并最大限度地减少了银离子损失.
涉及Ag+离子和ROS的协同作用破坏了生物膜,并诱导了核酸泄漏.
超偏磁性Ag@Fe3O4NP显示了10μg/mL的低最小抑制度 (MIC).
在40个磁回收周期后,在水处理模拟中100%的病原体消除.
从医疗导管中有效地通过磁导去除生物膜.

结论:

Ag@Fe3O4 NPs提供了一种有效和可持续的方法来对抗水中传播的病原体.
这些NP有效地消除了医疗器械中的生物膜.
该研究强调了Ag@Fe3O4NP在公共卫生和水安全方面的潜力.

关键词:

在Ag@Fe3O4 NP中使用.核心-外结构的核心-外结构回收再利用回收再利用这是生物膜的去除.处理水处理水的方法

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