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Updated: Mar 6, 2026

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一种异质体MT-CO2 m.8024G > 一种变体与线粒体生物能缺陷和光学缩有关

Jing Wu1, Cunhui Pan2, Ruowei Zhu3,4

  • 1Center for Rehabilitation Medicine, Department of Ophthalmology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.

Molecular neurobiology
|March 4, 2026
PubMed
概括

在MT-CO2中,一种新的线粒体DNA变体导致了Leber遗传性视神经病变 (LHON) 和渐进的视力丧失. 这项研究通过线粒体功能障碍和改变的线粒细胞衰竭将异质变体与光学缩联系起来.

关键词:
在MT-CO2中,二氧化碳线粒体复合体IV 线粒体复合体IV视力缩的光学缩视觉神经病变是一种视觉神经病变.

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