常规癌症护理中的创新运动:八年综合瘤运动疗法 (OTT) 的见解
Timo Sonntag1, Ariana Safi2, Vera Coutellier2
1Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany. timo.niels@uk-koeln.de.
Sports medicine - open
|March 4, 2026
概括
结构化瘤运动疗法 (OTT) 对癌症患者有好处,改善了身体表现和患者报告的结果. 增加运动出席率的策略对于在临床环境中最大限度地发挥这些积极影响至关重要.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 康复医学 康复医学 康复医学
背景情况:
- 运动对癌症患者的积极影响是公认的,但将结构化瘤运动纳入标准护理是具有挑战性的.
- 这项研究评估了一个监督的瘤运动治疗 (OTT) 计划,集成到临床护理中.
研究的目的:
- 评估患者的特征,运动参与以及OTT对患者报告结果 (PRO) 和身体表现的影响.
- 确定在标准临床环境中实施OTT的可行性和有效性.
主要方法:
- 一项观察性研究分析了2012年至2020年期间在OTT注册的1660名癌症患者的数据.
- 鼓励患者至少三个月参加个性化OTT,收集人口统计,病史和治疗数据.
- 运动出席率被追踪了长达一年,有效性通过力量/耐力测试和PROs (生活质量,疲劳,心理社会困扰) 在6至24周之间进行评估.
主要成果:
- 该研究包括1660名患者 (平均年龄54岁,70%为女性,40%为乳腺癌,80%没有转移).
- 只有32%的人经常炼 (平均19个会议超过19周),只有1%的人达到建议的每周≥2次会议.
- 观察到强度,耐力和PRO的改善,更大的好处与更高的炼参与度相关. 年龄较大和旅行距离较短与更好的出席率有关.
结论:
- 像OTT这样的创新炼计划可以整合到标准的医院癌症护理中.
- 现实世界的数据证实了运动对癌症患者的PRO和身体结果的有益影响.
- 提高运动出席率至关重要,以充分实现癌症患者实际运动干预措施的好处.
相关概念视频
Treatment Resistant Cancers
3.8K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.8K
Cancer Therapies
10.5K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.5K
Tumor Immunotherapy
2.1K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.1K
Adaptive Mechanisms in Cancer Cells
7.2K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
7.2K
Targeted Cancer Therapies
9.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
9.0K
Cancer Survival Analysis
806
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
806
