探索患者对上道泌尿道癌的看法:一个定性采访研究
Dina Filipenko1, Michael Acquadro2, Ola Ghatnekar3
1PPD Evidera Patient-Centered Research, Thermo Fisher Scientific, The Ark, 201 Talgarth Road, London, W6 8BJ, UK. Dina.Filipenko@thermofisher.com.
Oncology and therapy
|March 4, 2026
概括
这项研究基于患者的经验开发了上道泌尿道癌 (UTUC) 的概念性疾病模型. 它确定了关键的症状和影响,揭示了工人联合会护理的未满足需求.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 患者报告的结果
背景情况:
- 有限的患者数据存在于上道泌尿道癌 (UTUC) 的症状和影响.
- 了解患者的体验对于有效的UTUC管理至关重要.
研究的目的:
- 根据患者的经验,为UTUC开发一种概念性疾病模型 (CDM).
- 为了识别和捕捉UTUC特定的症状和影响在整个治疗连续.
主要方法:
- 一个有针对性的文献审查告知了面试指南的开发.
- 对15名UTUC患者进行了定性概念诱导采访.
- 专题分析采访成绩单和文献综合用于开发CDM.
主要成果:
- 患者报告了22种症状",尿液中的血"和"疲劳"是治疗前最常见的症状,以及治疗后的"疲劳"和"疼痛".
- UTUC及其治疗显著影响了情绪健康,日常活动,人际关系和社会功能.
- 开发了一个全面的CDM,详细说明了低级和高级UTUC的症状和影响.
结论:
- 这项研究突出了UTUC症状和治疗影响的广泛范围,强调了未满足的患者需求.
- 结果为选择临床试验终点和改进以患者为中心的UTUC护理策略提供了定性基础.
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