巴西乳发育缺陷的流行:系统性审查和元分析
C M M T Lopes1, L J S Falcão1, L M Lemos1
1Department of Dentistry, Federal University of Rio Grande do Norte, Natal, Brazil.
概括
在巴西,质发育缺陷 (DDE) 是常见的. 牙切口低矿化 (MIH) 和牙化显示出显著的患病率,因地理区域和年龄组而异.
科学领域:
- 牙科公共卫生 牙科公共卫生
- 流行病学 流行病学
- 儿科牙科 儿科牙科
背景情况:
- 牙面膜发育缺陷 (DDE) 包含各种影响牙结构的牙面膜异常.
- 摩尔切割器低矿化 (MIH),低矿化第二初级摩尔 (HSPM),牙面膜低化和牙化是具有潜在公共卫生影响的重大DDEs.
- 了解这些疾病在巴西的流行程度对于有针对性的干预至关重要.
研究的目的:
- 估计巴西人口中DDE的综合流行率,特别是MIH,HSPM,牙面膜低成形和牙化.
- 综合现有的流行病学数据关于巴西各地的DDE流行率.
- 确定可能导致DDE流行异质性的因素.
主要方法:
- 在多个数据库 (PubMed, Web of Science, Scopus, Embase, SciELO, LILACS) 和灰色文献 (Google Scholar) 中进行了系统的文献搜索.
- 包括报告巴西DDE流行率的横截面研究,遵守PRISMA指南.
- 对58项研究 (42,337名参与者) 的数据进行了随机效应元分析,并使用Joanna Briggs Institute检查清单评估了偏差风险.
主要成果:
- 综合的患病率估计为:MIH 15.6%,HSPM 12.5%,牙质低成形4.5%,牙化 18.3%.
- 观察到显著的异质性 (I2 > 95%),地理位置被确定为主要变化来源 (p < 0.001).
- 牙甲的低成形在初级牙 (10.4%) 比永久牙 (2.9%) 更为普遍,而牙化在永久牙 (22%) 比初级牙 (11.2%) 更为普遍.
结论:
- 质发育缺陷 (DDE) 在巴西是一个相当大的公共卫生问题.
- 地理区域和牙类型 (初级或永久) 显著影响特定DDEs的流行率.
- 进一步的研究和有针对性的公共卫生战略是有必要的,以解决巴西DDEs的高患病率.
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