年轻的成年人物质使用作为一个预测者 糟糕的自我评价记忆几十年后在中年期
Megan E Patrick1, Yuk C Pang1, Yvonne M Terry-McElrath1
1Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Journal of aging and health
|March 4, 2026
概括
在年轻成年期使用重物质与晚年记忆力低下有关. 中年早期的物质使用障碍症状完全介绍了饮酒和大麻的这种联系,但没有吸烟.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 精神病学是一个精神病学.
背景情况:
- 年轻成年人吸毒是一个日益严重的公共卫生问题.
- 中年和晚年认知衰退会影响生活质量.
- 了解早期物质使用对认知的长期影响至关重要.
研究的目的:
- 调查年轻人大量使用物质和中年后期自我评价记忆之间的纵向关系.
- 确定中年早期的有问题的物质使用是否调解了这些关联.
主要方法:
- 利用了"监测未来纵向小组研究"的数据.
- 包括50-65岁 (2018-2023年) 的参与者,数据来自18岁 (1976-1991年).
- 分析了年轻成年人物质使用和中年后期记忆之间的关联,并对中年早期物质使用障碍症状进行调解分析.
主要成果:
- 年轻人大量使用所有物质直接与中年后期自我评价记忆不良的几率增加有关.
- 中年早期的物质使用障碍症状完全调解了过度饮酒和大麻使用的关联.
- 在每日一包香烟的吸烟中没有观察到调解.
结论:
- 从年轻成人开始持续使用重物质,作为认知能力下降的累积风险因素.
- 对风险因素的终身检查,包括物质使用,对于早期识别认知能力下降风险至关重要.
- 针对年轻和中年早期物质使用的干预措施可能会减轻长期的认知风险.
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