母亲产前和产后抑郁和焦虑:对儿童喘及其表型的影响
Eetu Kanerva1, Minna Lukkarinen2, Marika Leppänen3
1Department of Adolescent Psychiatry, University of Turku, and Turku University Hospital, Turku, Finland.
孕妇在怀孕期间和分娩后的抑郁和焦虑障碍会增加后代的喘风险. 产后母亲的心理健康问题显示,与儿童的亚托皮性和非亚托皮性喘表型有显著的关联.
科学领域:
- 生殖精神病学是一种精神病学.
- 儿科过敏和免疫学
- 公共卫生 公共卫生
背景情况:
- 怀孕期间母亲的心理压力与后代喘风险增加有关.
- 具体的时间和母亲的痛苦对后代喘的影响仍然不清楚.
研究的目的:
- 评估母亲产前和产后抑郁和焦虑障碍对后代喘的影响.
- 分析这些影响纵向和喘表型 (过敏与非过敏).
主要方法:
- 使用了310,701名儿童和232,240名母亲的医疗保健登记数据.
- 确定的母亲抑郁症 (F30-F38) 和焦虑症 (F40-F48) 疾病.
- 评估产前 (产前1年) 和产后 (产后3年) 障碍的时间.
- 在7-12岁时检查了整体喘 (J45-J46) 和表型 (J45.0,J45.1).
主要成果:
- 母亲产前抑郁和焦虑与儿童整体喘增加有关.
- 产后母亲焦虑障碍与阿托皮性喘和非阿托皮性喘有关.
- 产后母亲的抑郁和焦虑障碍与非性喘有关.
- 孕产妇疾病的时间和持续性并没有显著改变这些关联.
结论:
- 孕产妇的抑郁和焦虑障碍与后代的喘有关,具有时间和表型特异性的影响.
- 产后母亲心理健康障碍对儿童的呼吸系统健康有重大影响.
- 独特的途径可能是母亲心理健康和儿童喘之间的关系的基础.
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