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帕索斯-乳酸盐评分:一种新的预后工具,用于预测急性肺栓塞的住院死亡率

Ekrem Taha Sert¹, Kamil Kokulu¹, Oğuz Yürük¹

¹Department of Emergency Medicine, Aksaray University Medical School, Aksaray, Turkey.

Heart & lung : the journal of critical care

|March 4, 2026

概括

新的PATHOS-Lactate评分准确地预测了急性肺栓塞 (PE) 患者的住院死亡率. 这种简单的综合指数比现有的早期风险评估模型提供了优越的预测性能.

科学领域:

心脏病学心脏病学
肺部病理学肺部病理学
紧急医疗紧急医疗

背景情况:

准确的早期死亡风险分层对于急性肺栓塞 (PE) 管理至关重要.
现有的PE风险评估工具可能需要改进,以提高预后准确度.

研究的目的:

评估PATHOS-Lactate评分的预后能力,这是一个新的复合指数,用于预测PE患者的住院死亡率.
将PATHOS-乳酸盐评分的表现与已建立的风险指标进行比较,例如简化肺栓塞严重性指数 (sPESI) 和PATHOS评分.

主要方法:

通过CTPA诊断的203名成年PE患者的回顾性分析.
使用逻辑回归计算PATHOS-乳酸盐得分:0.685 × PATHOS + 0.314 × 乳酸盐 (mmol/L).
接收器操作特征 (ROC) 曲线分析,以比较各种分数和乳酸水平的预后准确性.

主要成果:

与sPESI,PATHOS和单独的乳酸相比,PATHOS-乳酸得分显示出更好的区分性能 (AUC=0.842).
该得分显示高灵敏度 (74.1%) 和特异性 (84.0%),截止值为3.4.
在多变量分析中证实了PATHOS-Lactate得分与住院死亡率 (OR:2.90,p < 0.001) 的独立关联.

结论:

帕索斯-乳酸盐评分为PE早期死亡风险评估提供了更高的预后准确性.
这个得分,利用简单和可访问的参数,为临床医生提供了一个实用的工具.
这些发现支持PATHOS-Lactate评分作为现有的PE风险分层策略的宝贵补充.

关键词:

在PATHOS的得分中,PATHOS的得分是什么?肺栓塞肺栓塞是一种肺栓塞.简化肺栓塞重度指数简化肺栓塞重度指数乳酸乳酸是一种乳酸.死亡率死亡率

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