在多张床位病房中通过感染变种传播SARS CoV-2传播的可能性
Anoshé Aslam1, Judy Yan1, Shauna Usiak1
1Infection Prevention & Control, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
The Journal of hospital infection
|March 4, 2026
概括
医院房间共享导致COVID-19患者的17%的二次感染率. 一半的感染无症状,攻击率在各个变体中保持一致.
科学领域:
- 传染性疾病 传染性疾病
- 医院流行病学 医院流行病学
- 在瘤学瘤学.
背景情况:
- 医院发作的COVID-19 (HO-COVID-19) 对脆弱患者群体构成重大风险.
- 了解医疗保健机构内的传播动态对于感染控制至关重要.
研究的目的:
- 为了调查HO-COVID-19患者的室友之间的二次感染率.
- 分析暴露室友感染的临床表现和严重程度.
- 为了比较Omicron变异激增之前和之后的感染攻击率.
主要方法:
- 在癌症中心对304例HO-COVID-19病例 (2021-2024) 的回顾性分析.
- 鉴定了299名患者室友在指数病例的传染期暴露.
- 计算二次感染率,评估无症状和严重感染比例,并比较不同时期的发作率.
主要成果:
- 在299名室友中,有17% (51) 获得了二次感染.
- 50%的二次感染是无症状的.
- 十二% (12%) 的二次感染进展为严重的疾病.
- 在Omicron前期和后期,二次感染发作率没有显著差异.
结论:
- 在医院共用房间对COVID-19传播具有显著的风险.
- 很大一部分二次感染是无症状的,这凸显了识别和隔离传染个体的挑战.
- 奥米克朗的出现并没有改变这个医院环境中的传播动态.
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