皮肤肌肉炎伪装成血管:一个关键的差异,不要忽视
Kevin Chan1, Gemma Kwan2, Hwei Choo Soh3
1Department of Immunology, Liverpool Hospital, Liverpool, New South Wales, Australia kevin.chan2@health.nsw.gov.au.
BMJ case reports
|March 4, 2026
概括
皮质神经炎是一种罕见的自身免疫性疾病,可以出现不寻常的部胀. 早期诊断和免疫抑制对于管理这种情况和预防进一步的器官损伤至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
背景情况:
- 皮质肌炎是一种罕见的自身免疫性疾病,影响皮肤,肌肉和呼吸系统.
- 及时免疫抑制对于管理皮肤肌炎至关重要,以防止疾病进展和多器官损伤.
研究的目的:
- 报告一个不寻常的表现皮肤肌炎与部胀.
- 强调在异常呈现时考虑皮肤肌炎的重要性.
主要方法:
- 一个40多岁的男性患者的临床病例报告,出现严重的部胀.
- 诊断工作包括肌酸激酶水平,自身抗体测试 (SAE1) 和肌肉活检.
主要成果:
- 部胀并没有归因于感染或血管.
- 该患者被诊断患有皮肤肌炎,由阳性SAE1自身抗体和肌肉活检结果证实.
- 演示包括消化不良和显著的肌肉参与.
结论:
- 子胀可能是皮肤肌炎的非典型,非海斯坦胺/布拉迪基宁介导的表现.
- 早期识别和治疗皮肤肌炎是必不可少的,即使有不寻常的症状.
相关概念视频
Myocarditis II: Clinical Features and Diagnostic Tests
392
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
392
Myocarditis I: Introduction
520
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
520
Myasthenia Gravis: Overview and Treatment
3.2K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
3.2K
Myocarditis III: Medical Management
274
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
274
Papillary Dermis
6.4K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
6.4K
Skin Diseases and Disorders
5.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.9K


