周围T细胞淋巴瘤-NOS呈现出空腔肺病变,模仿侵入性阿斯伯吉洛症
Jose Lopez Ventosa1, Aida Rodriguez2, Noelia Garcia3
1Internal Medicine, Universidad de Puerto Rico Recinto de Ciencias Médicas, San Juan, Puerto Rico, USA Jose.lopez87@upr.edu.
BMJ case reports
|March 4, 2026
概括
一种罕见的癌症,外围T细胞淋巴瘤 (PTCL-NOS),可以模仿真菌感染. 这种病例显示PTCL-NOS呈现肺部和大脑病变,最初被误认为是阿斯伯吉洛症.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 周围T细胞淋巴瘤,未另有说明 (PTCL-NOS) 是一种罕见的非霍奇金淋巴瘤.
- PTCL-NOS通常涉及多个器官,提出诊断挑战.
- 罕见的表现可以模仿其他疾病,使诊断复杂化.
研究的目的:
- 报告一个独特的PTCL-NOS病例与不寻常的器官参与.
- 为了突出诊断在区分PTCL-NOS和侵入性真菌感染的诊断困难.
- 强调组织病理学在诊断罕见瘤病的重要性.
主要方法:
- 一个40多岁的女性患者的病例报告.
- 临床表现包括耳炎,脑,双侧腔腔肺病变.
- 诊断工作包括成像,血清标记物 (银曼南) 和组织活检.
- 组织病理学检查对于确定诊断至关重要.
主要成果:
- 最初的呈现模仿了传播的阿斯珀吉洛斯病,导致经验性抗真菌治疗.
- 血清银河门阳性,支持最初的真菌感染假说.
- 组织活检对真菌元素呈阴性.
- 组织病理学最终证实PTCL-NOS作为诊断.
结论:
- PTCL-NOS可能会出现广泛的肺部和中枢神经系统参与.
- PTCL-NOS的临床表现可能与侵入性真菌病非常相似.
- 准确的组织病理学分析对于诊断PTCL-NOS的非典型表现至关重要.
更多相关视频
09:52Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
11.1K
15:01Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
Published on: September 18, 2021
3.9K
相关概念视频
01:28Pulmonary Tuberculosis II
1.8K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.8K
01:31Pulmonary Tuberculosis III
1.2K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
1.2K
01:17Other Pulmonary Disorders
1.8K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.8K
01:28Pulmonary Tuberculosis V
704
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
704