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慢性髓性白血病 (CML) 在怀孕期间呈现为无症状白血细胞瘤

Sowmya Koteshwara¹, Krishna Madhuri Gadde², Mahesh Rajashekaraiah³

¹OBG, JSS ACCADEMY OF HIGHER EDUCATION AND RESEARCH, Mysuru, Karnataka, India sowmyak@jssuni.edu.in.

BMJ case reports

|March 4, 2026

概括

怀孕期间白细胞数量明显升高需要对慢性髓性白血病 (CML) 等严重疾病进行评估. 这一案例突出了怀孕期间的保守管理,随后是产后CML治疗.

科学领域:

血液学血液学血液学
在瘤学瘤学.
产科产科产科产科产科

背景情况:

在怀孕期间,轻微的白细胞瘤是常见的.
显著升高的白细胞计数需要对潜在的病理进行调查,包括白血病.
慢性髓性白血病 (CML) 在年轻人群中越来越多地被诊断出.

研究的目的:

报告一个诊断为慢性髓性白血病的病例,该病例发生在一个近期的孕妇患者身上.
讨论怀孕期间CML的管理.
为了强调怀孕期间监测白细胞数量的重要性.

主要方法:

一个30多岁的女性的病例报告,在预产时呈现出无症状的明显白细胞瘤.
保守的管理包括分娩,然后是分娩后启动最终的CML治疗.

主要成果:

该患者被诊断患有慢性髓性白血病 (CML).
由于患者的晚期怀孕,分娩经过了保守的管理.
最终的CML治疗是在分娩后开始的.

结论:

在怀孕期间迅速评估明显增加的白细胞计数对于排除CML等病理原因至关重要.
在怀孕期间管理CML会带来独特的治疗挑战.
在怀孕期间,基线和序列白细胞监测非常重要.

关键词:

慢性髓性白血病慢性髓性白血病血清细胞溶解症血清细胞溶解症氨酸激酶抑制剂氨酸激酶抑制剂

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