身体活动降低了糖尿病患者外围神经病变的可能性
Evan L Reynolds1, David Russman2, Georgios Baskozos3
1Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA reyno335@msu.edu.
Journal of neurology, neurosurgery, and psychiatry
|March 4, 2026
概括
增加体力活动 (PA) 降低了糖尿病外围神经病变 (DPN) 的风险. 对于女性来说,更高的PA也降低了疼痛性DPN (pDPN) 的几率.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 运动医学 运动医学
背景情况:
- 临床指南建议身体活动 (PA) 预防糖尿病外围神经病变 (DPN).
- 目前的建议缺乏关于最佳PA强度和持续时间的具体指导.
- 本研究研究了PA水平和DPN/疼痛性DPN (pDPN) 之间的关系.
研究的目的:
- 为了确定身体活动,糖尿病外围神经病变和疼痛性糖尿病外围神经病变之间的关联.
- 在DPN管理中提供基于证据的PA建议.
主要方法:
- 一项涉及2878名糖尿病患者的横截面研究.
- 使用手腕穿戴的加速度计测量身体活动,将强度分类为轻度,中度或强度.
- 糖尿病外围神经病变 (DPN) 和疼痛性DPN (pDPN) 用密歇根神经病查仪器和自我报告的脚痛进行评估.
主要成果:
- 超过75毫克的时间与降低DPN几率 (OR0.97) 有关.
- 适度 (OR 0.95) 和强烈 (OR 0.40) 的PA水平显著降低了DPN的几率.
- 在50mG以上的增加的PA降低了女性的pDPN几率 (OR0.92),但不是整体.
结论:
- 较高的体力活动与较低的DPN发病率有关.
- 在女性中,增加的PA也与pDPN的可能性降低相关.
- 需要进一步的研究来确定PA和DPN发展之间的因果关系.
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