通过深度神经网络架构测量的内脏脂肪组织与慢性病之间的关联
Goh Eun Chung1,2, Ji Won Yoon1, Huiyeon Kim3
1Department of Internal Medicine, Healthcare Research Institute, Gangnam Healthcare Center, Seoul National University Hospital, Seoul, Republic of Korea.
Scientific reports
|March 4, 2026
概括
这项研究表明,内脏脂肪组织 (VAT) 增加了两性慢性病 (CKD) 的风险,而皮下脂肪组织 (SAT) 显示了性别特定的关联. 对腹部CT扫描的AI分析有助于评估CKD风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 放射学 放射学是一门学科.
- 人工智能的人工智能
背景情况:
- 慢性病 (CKD) 的患病率正在全球范围内上升.
- 腹部肥胖是一种已知的CKD风险因素.
- 准确评估腹部脂肪分布对于风险分层至关重要.
研究的目的:
- 调查腹部脂肪量与CKD之间的关联.
- 评估基于人工智能的CT图像分析对评估腹部脂肪的有用性.
- 探索腹部脂肪和CKD之间的关系的性别特异性差异.
主要方法:
- 利用了14,105名韩国人的健康检查数据,进行了腹部CT扫描.
- 采用深度神经网络架构和人工智能软件来测量内脏脂肪组织 (VAT) 和皮下脂肪组织 (SAT) 的体积.
- 进行了多变量逻辑回归分析,以评估腹部脂肪量与CKD风险之间的关联,并对潜在的混因素进行调整.
主要成果:
- 内脏脂肪组织 (VAT) 体积与男性 (OR 1.25) 和女性 (OR 1.18) 两种类型的CKD风险增加有显著的关联.
- 皮下脂肪组织 (SAT) 体积显示女性的CKD风险与逆相关性 (OR 0.77),但男性的阳性相关性 (OR 1.09).
- 增值税/增值税比率与男性的CKD风险增加显著相关 (OR 1.09).
结论:
- 腹部脂肪量,特别是增值税,以性别特定的方式独立地与CKD风险相关.
- 用人工智能驱动的腹部CT扫描分析为早期CKD检测和风险分层提供了一个有希望的工具.
- 了解性别特异性的脂肪分布模式对于有效的CKD风险评估至关重要.
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