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Updated: Mar 6, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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埃斯基塔洛普拉姆通过受损的IIS/自信号通路加速衰老

Zi-Yi Chen1, Cao-Yan Qi1, Ji Feng1

  • 1Department of Occupational Health and Toxicology, School of Public Health, Fudan University, 130 Dong-An Road, Shanghai, 200032, China.

GeroScience
|March 4, 2026
PubMed
概括

埃斯基塔洛普拉姆是一种常见的抗抑郁药,可以加速老化,并缩短模型生物的寿命. 这种促衰老效应源于胰岛素/IGF-1信号和自的受损,与其他SSRI相反.

关键词:
凯诺哈比迪斯 (Caenorhabditis elegans) 是一个可爱的植物.衰老的衰老 衰老的衰老自自是一种自的过程.埃斯基塔洛普拉姆 (escitalopram) 是一种药物.胰岛素类生长因子I

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