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Updated: Mar 6, 2026

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Published on: May 13, 2019

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流感聚合酶的共同转录帽抢夺机制

Alexander Helmut Rotsch1, Delong Li1,2, Maud Dupont3

  • 1Department of Molecular Biology, Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany.

Nature
|March 4, 2026
PubMed
概括

流感病毒的 cap-dependent mRNA 生产依赖于由病毒RNA-dependent RNA聚合酶 (FluPol) 的 cap snatching. 冷-EM结构揭示了FluPol如何与宿主RNA聚合酶II相互作用,分裂并获得用于病毒转录的封闭RNA片段.

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