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Updated: Mar 6, 2026

Isolation and Culture of Primary Mouse Keratinocytes from Neonatal and Adult Mouse Skin
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来自 keratinocytes 的代谢警报剂增强了系统性幽默免疫力

Zhenglin Ji1,2, Ji Gao1, Shaocun Zhang3

  • 1State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua-Peking Center for Life Sciences, Institute for Immunology, China Ministry of Education Key Laboratory of Protein Sciences, Tsinghua University, Beijing, China.

Nature
|March 4, 2026
PubMed
概括

酸法尼西尔 (Farnesyl pyrophosphate,FPP) 作为一种内源性警报剂,通过皮肤细胞促进IgG抗体的产生. 这一途径增强了免疫反应,并为全身性红斑狼 (SLE) 提供了新的疫苗和治疗方法的潜力.

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