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Updated: Mar 6, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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Published on: August 24, 2013

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表型多样性是由两个SNAREopathy基因之间的非线性遗传相互作用引起的

Jovana Kovačević1, Sébastien Houy2, Johny Pires1

  • 1Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit (VU) Amsterdam, De Boelelaan 1085, Amsterdam, 1081 HV, the Netherlands.

Molecular psychiatry
|March 4, 2026
PubMed
概括

遗传相互作用解释了大脑疾病中的症状多样性. 结合相互作用基因的突变,如那些导致SNARE病变的基因,导致不同的结果,从严重的发作到没有症状,在小鼠模型中.

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