氧气喷气CPAP:一种无电的低成本紧急呼吸辅助装置
Md Kawsar Ahmed1, Kaisar Ahmed Alman1, Meemnur Rashid1
1Department of Biomedical Engineering, Bangladesh University of Engineering and Technology (BUET), Dhaka, Bangladesh.
一种新的低成本,3D打印的持续正气道压力 (CPAP) 装置OxyJet,在资源有限的环境中提供有效的呼吸支持. 这种无电的设备显示了与标准CPAP相似的结果,改善了缺血患者的氧和度.
科学领域:
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
- 呼吸系统医学 呼吸系统医学
背景情况:
- 资源有限的环境面临着昂贵而复杂的重症监护室 (ICU) 呼吸辅助设备的挑战.
- 非侵入性呼吸辅助设备对于减少ICU入院至关重要,但在资源较少的地区往往无法获得.
- 需要在ICU以外的负担得起,便携和用户友好的呼吸辅助解决方案.
研究的目的:
- 设计和验证OxyJet,一个低成本的,便携式的,无电的3D打印连续正气道压力 (CPAP) 装置.
- 评估OxyJet在资源有限的环境中提供非侵入性呼吸辅助的可行性和生理效应.
- 为了比较OxyJet与标准CPAP系统在改善氧和度方面的有效性.
主要方法:
- 氧气喷气机的设计采用现成的部件和3D打印技术,灵感来自气体喷气机械.
- 基板测试是按照UK-MHRA RMCPAP指南进行的.
- 人类初步测试涉及健康志愿者和缺血患者,随后在孟加拉国达卡进行了试点可行性研究,将OxyJet与标准CPAP进行比较.
主要成果:
- 氧气喷气提供高流量 (高达65L/分钟),PEEP (5-15cmH2O) 和FiO2 (高达100%),成本低于类似系统的10%.
- 实验室测试和初步人体试验证明了该设备的安全性和可用性.
- 一项对23名低血症患者的试点研究显示,与标准CPAP相比,外周氧和 (SpO2) 的显著改善 (OxyJet的平均SpO2增加为12.0%,标准CPAP的平均增加为11.5%).
结论:
- 氧气喷射CPAP的可行性和短期生理效果与标准CPAP系统相美.
- 该设备有可能在ICU外作为紧急呼吸辅助解决方案.
- 通过提供可访问的呼吸护理,OxyJet可以加强资源有限的环境中的医疗保健系统.
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