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Updated: Mar 6, 2026

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揭示了致病性误解突变对男性蛋白质功能的动态中介影响

Qian Zhang1, Yinghao Guo2, Hao Wang1

  • 1Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin 150081, China.

The journal of physical chemistry letters
|March 5, 2026
PubMed
概括

致病误解突变 (DCMMs) 改变了蛋白质的动态,而不仅仅是稳定性. 这些突变通过影响全性通路来破坏蛋白质相互作用,突显了研究蛋白质动态的必要性,以了解突变效应.

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