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在猫中,结节性肺炎与贝斯诺伊蒂亚·达林基感染相关
Jaspreet Kaur1, Darian Giannino1, Ryan Taylor1
1Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
概括
这项研究报告了第一例已知由Besnoitia darlingi引起的猫类肺炎病例. 分子诊断确定了原生动物生物,将其与Toxoplasma gondii区分开来.
科学领域:
- 兽医病理学 兽医病理学
- 寄生虫学的寄生虫学
- 猫科动物医学 猫科动物医学
背景情况:
- 猫类肺炎可能有各种原因,包括传染病原体.
- 原生动物感染是猫的炎症性肺病的差异诊断.
- 区分相似的原生动物有机体可能具有挑战性.
研究的目的:
- 在国内短毛猫中识别发炎性肺炎的致病原体.
- 为了区分内部的原生动物生物与Toxoplasma gondii.
- 报告与Besnoitia darlingi相关的猫类肺炎的第一个病例.
主要方法:
- 肺叶的放射性检查. 肺叶的放射性检查.
- 肺组织的细胞学和组织学检查.
- 聚合酶连锁反应 (PCR) 测定针对18S DNA和ITS1 DNA标记物的测定.
- 桑格测序用于分子识别.
主要成果:
- 射线图显示右尾部和中部肺叶的巩固.
- 组织病理学揭示了原生动物有机体的炎症性炎症.
- 分子分析确定这些生物体是Besnoitia darlingi,与Toxoplasma gondii不同.
结论:
- 在猫类肺炎中应考虑Besnoitia darlingi感染,而猫类肺炎中应考虑 pyogranulomatous 炎症.
- 分子方法对于准确识别猫的原生动物病原体至关重要.
- 这是Besnoitia darlingi在猫科动物中引起肺炎的首例报告.
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