通过红外传感器检测口腔状细胞癌的非侵入性诊断方式
Shahrzad Rahimizadeh Nahavandi1, Arghavan Tonkaboni2,3, Soheila Manifar2
1Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, Vancouver, Canada.
Cancer reports (Hoboken, N.J.)
|March 5, 2026
概括
早期检测口腔状细胞癌 (OSCC) 是至关重要的. 一种新型的红外设备非侵入性地测量口内温度差异,在识别可疑病变方面显示出高精度.
科学领域:
- 在瘤学瘤学.
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 口腔状细胞癌 (OSCC) 是口腔和面部区域的一个流行恶性瘤.
- 晚期诊断显著降低OSCC的生存率,突出了改善早期检测方法的需要.
- 目前的诊断方法往往缺乏早期检测的非侵入性功能.
研究的目的:
- 开发和评估一种用于非侵入性OSCC检测的新型口腔内红外装置.
- 测量癌症组织和健康的口腔粘膜之间的温度差异.
- 为了评估OSCC的红外热学的诊断准确性.
主要方法:
- 一个定制的口腔内红外设备被设计和制造.
- 招募了20名参与者 (10名OSCC患者,10名健康对照).
- 使用该设备测量组织温度,并使用t测试和ROC曲线分析数据.
主要成果:
- 在OSCC患者的瘤组织和健康的粘膜之间发现了统计学上显著的温度差异 (p < 0.001).
- 温度差>0.97°C显示出100%的灵敏度和特异性来检测潜在的病变.
- 温度>38.42°C表明潜在的恶性病变,具有100%的灵敏度和90%的特异性.
结论:
- 红外热学是一种有效的非侵入性工具,用于检测可疑的口腔病变.
- 开发的设备有助于通过热变量分析早期检测OSCC.
- 这项技术为及时和准确的口腔癌诊断提供了一个有希望的途径.
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