可生物降解胰腺支架的成本效益和有效性,用于预防ERCP后胰腺炎:一项回顾性多中心研究
Vicki McGarrigle1, Yuto Shimamura1, Leonardo Zorron Cheng Tao Pu1
1Department of Gastroenterology and Hepatology Austin Health Melbourne Australia.
概括
可生物降解的胰腺支架在预防ERCP后胰腺炎方面是安全有效的,通过消除取回程序,可以大大节省成本.
科学领域:
- 胃肠病学 胃肠病学
- 医疗器械 医疗器械
- 卫生经济学 卫生经济学
背景情况:
- 后内镜逆行性胆固醇细胞造影 (ERCP) 胰腺炎 (PEP) 影响高达10%的患者.
- 用于PEP预防的塑料支架需要移除,增加成本和患者负担.
- 可生物降解的支架消除了检索需求,但临床和经济数据有限.
研究的目的:
- 评估可生物降解的胰腺支架与用于PEP预防的塑料支架的成本效益.
- 评估临床结果,包括PEP发生率和技术成功率.
主要方法:
- 对111名使用可生物降解胰腺支架进行ERCP的成年患者进行了回顾性队列研究.
- 对每位患者的成本和PEP发生率与塑料支架的历史数据进行比较.
- 数据收集包括人口统计,程序细节和临床结果.
主要成果:
- 可生物降解的支架证明了每名患者的成本节约为393澳元 (p=0.002).
- 技术成功率为98%,使用方便性与塑料支架相美.
- PEP发病率为11%,在接受抗凝药或有PEP病史的患者中发病率更高.
结论:
- 可生物降解的胰腺支架放置在技术上是安全和有效的PEP预防.
- 这些支架可大大节省成本,并降低患者/医疗保健负担.
- 观察到的PEP率与高风险患者群体一致.
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