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Updated: Jul 6, 2026

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

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综合性RNA-seq分析揭示了与免疫相关的枢纽基因NR4A1和FOSB在重复性自发性流产中:生物信息学研究

Kosar Babaei1, Saman Morovat2, Hossein Mozdarani3

  • 1Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.

International journal of reproductive biomedicine
|March 5, 2026
PubMed
概括

复发性自发性流产 (RSA) 涉及1%至5%的女性. 这项研究确定NR4A1和FOSB是RSA中关键的下调基因,表明它们在免疫功能障碍和潜在治疗点中的作用.

关键词:
这就是FOSB.基因表达特征分析NR4A1.1. 这里是NR4A1.1.蛋白相互作用映射蛋白质相互作用映射自发流产是一种自发的流产.

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Author Spotlight: Advancing Reproductive Immunology with a Protocol for the Quantitative Evaluation of Endometrial Immune Cells07:46

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...