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Updated: Mar 6, 2026

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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彻底改变蛋白质降解:利用纳米颗粒来提供PROTAC

Yonghang Fan1, Jianfen Su1, Jun Yang2

  • 1The Affiliated Panyu Central Hospital, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, Guangdong Basic Research Center of Excellence for Respiratory Medicine, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, PR China.

Materials today. Bio
|March 5, 2026
PubMed
概括

化向的仿真体 (PROTACs) 提供了新的药物发现途径,但面临着交付挑战. 纳米医学增强了PROTAC的生物可用性和特异性,加速了各种疾病的临床转化.

关键词:
药物交付是药物交付的过程.纳米粒子输送系统提供系统.这就是PROTAC.精密疗法是一种精确的疗法.有针对性的蛋白质降解降解.

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