截肢者患有糖尿病和血管疾病的下肢骨质整合
Jason S Hoellwarth1, LaYow C Yu1, Tyler D DeSena1
1Limb Lengthening and Complex Reconstruction Service, Osseointegration Limb Replacement Center, Hospital for Special Surgery, New York, NY.
概括
骨整合在患有糖尿病 (DM) 和外周血管疾病 (PVD) 的截肢者中显示出有希望的安全性和有效性. 患者在结局和运动能力方面经历了显著的改善,并有可管理的并发症.
科学领域:
- 整形外科手术 整形外科手术
- 假肢和整形手术
- 康复医学 康复医学 康复医学
背景情况:
- 糖尿病 (DM) 和外周血管疾病 (PVD) 是截肢者常见的并发症.
- 这些情况可能会使假肢安装和康复复复杂化.
- 骨整合为改善假肢整合提供了一个潜在的替代方案.
研究的目的:
- 评估DM和/或PVD截肢者骨质整合的结果.
- 在这个患者群体中评估骨整合的安全性和有效性.
- 分析患者报告的结果和骨整合后的运动性能.
主要方法:
- 一个案例系列设计在一个城市三级推学术医疗中心被采用.
- 五名患者 (1名患有DM,3名患有PVD,1名患有两种疾病,4名穿骨,1名穿骨) 接受了按压整合骨质整合的修复截肢手术.
- 随访持续时间为4.1±0.3年,主要结局包括不良事件和二次结局包括PROM和流动性.
主要成果:
- 没有发生植入物松,骨折,全身并发症或死亡.
- 一名患者需要为骨髓炎进行脱bridement;两名患者接受了皮肤改造.
- 所有患者在患者报告的结果指标 (PROM) 和流动性 (至少一个K级增加) 均显著改善.
结论:
- 骨质整合是一种潜在的安全和有效的选择,用于选择患有DM和/或PVD的截肢者.
- 虽然可能会出现感染和皮肤冗余等并发症,但它们似乎是可以控制的.
- 骨整合可以在这个具有挑战性的患者群体中优化康复和假肢使用.
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