长期使用线索利德后双边视神经病变:一个病例报告
Hadiza Ometere Ibrahim1, Aaesha Easa Alnuaimi2, Amani Alzaabi3
1Department of Internal Medicine, Zayed Military Hospital, Abu Dhabi, United Arab Emirates.
IDCases
|March 5, 2026
概括
长时间的线索利德治疗可能会导致视神经病变,导致视力丧失. 早期检测和干预对于潜在的恢复至关重要,强调在长期治疗期间需要定期进行眼科检查.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 神经学 神经学
背景情况:
- 林氏素是一种用于严重感染的抗生素,包括由Mycobacterium所引起的.
- 长时间使用线索利德与视神经病变有关,这是一种影响视神经的疾病.
- 早期识别和干预对于管理与线索利德相关的视神经病变至关重要.
研究的目的:
- 报告双边线索利德相关的视神经病变.
- 强调早期诊断和管理这种并发症的重要性.
- 强调需要长期治疗linezolid的患者进行眼科监测.
主要方法:
- 一个65岁妇女的案例研究,因为Mycobacterium疹感染而接受治疗.
- 眼科检查,包括视觉唤起的潜能和光学连贯性断层扫描.
- 神经成像以排除视力下降的其他原因.
- 停止使用linezolid和经验性皮质类固醇治疗.
- 为部分视力改善而进行白内障提取.
主要成果:
- 患者在线索利德治疗>6个月后出现了渐进的,无痛的双边视力下降.
- 眼科发现包括光盘,色彩视觉障碍和长时间视觉唤起的潜在延迟.
- 光学连贯断层扫描显示视网膜神经纤维层变厚,随后出现光学缩.
- 在白内障提取后出现了部分视力改善,但残留缺陷仍然存在.
结论:
- 莱涅佐利德相关的视神经病变是长期治疗的未被认可的并发症.
- 建议在接受线索利德超过推持续时间的患者进行例行眼科监测.
- 要避免误诊和不可逆转的视力损伤,需要高的怀疑指数.
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