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Updated: Mar 6, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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通过多站位酸化,ERK抑制了Capicua抑制器的功能

Sayantanee Paul1,2, Khandan Ilkhani1, Nathan Strozewski1

  • 1Department of Biology, University of Massachusetts Boston, Boston, MA 02125, USA.

Journal of cell science
|March 5, 2026
PubMed
概括

细胞外信号调节激酶 (ERK) 信号调节细胞生长和存活. 这项研究确定了Capicua (Cic) 蛋白的关键酸化部位,揭示了ERK如何控制Cic活动和降解.

关键词:
卡皮克瓦 (Capicua) 是一个古老的植物.这种植物是Drosophila.埃尔克·埃尔克是什么意思多站点酸化的方法酸盐的降解发生在酸盐中

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