塑造光滑肌肉力量:在尿路光滑肌肉中预制的作用
Simon Kiem1, Stefan Papenkort1, Mischa Borsdorf1
1Institute of Sport and Movement Science, Department of Motion and Exercise Science, University of Stuttgart, Stuttgart, Germany.
预先调整光滑肌肉 (SM) 影响机械测试. 自由收缩 (PFC) 预条件将猪膀SM中的被动力变化最小化,提高了实验可靠性.
科学领域:
- 生物力学 生物力学
- 生物材料是一种生物材料.
- 顺滑肌肉生理学 顺滑肌肉生理学
背景情况:
- 平滑肌肉 (SM) 机械适应挑战实验可重现性和生物机械建模.
- 预先调节协议用于稳定SM机械反应,但它们对组织特性和数据可变性的影响尚不清楚.
研究的目的:
- 为了比较三种预调节例程 - - 被动循环 (PCYC),无预调 (PNPC) 和自由收缩 (PFC) - - 对猪膀 (UB) SM的活性和被动力反应的影响.
- 评估预条件对SM机械测试中的数据变异性的影响.
主要方法:
- 猪尿膀SM组织条被随机分配到PCYC,PNPC或PFC程序中.
- 为了评估主动和被动力发展,采用了涉及被动拉伸坡道和两个同度收缩 (IC1,IC2) 的相同协议.
主要成果:
- PCYC导致了最高的主动和被动张力,但也产生了最高的主动张力变量.
- 在PNPC中,活性张力变异率最低 (CV=45%).
- PFC表现出最小的被动张力变异 (CV = 57%) 并有望防止爬行诱导的延长.
结论:
- 预先调节方案的选择显著影响SM组织观察到的机械性质.
- PFC预条件为减少被动力变异性和提高SM研究的一致性提供了一个有希望的策略.
- 定制的预条件化策略对于提高SM研究和器官建模的可靠性和可比性至关重要.
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