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Katsumi Mizuno^1,2, Miori Tanaka², Midori Date²

¹Showa University School of Medicine, Tokyo, Japan.

Journal of human lactation : official journal of International Lactation Consultant Association

|March 5, 2026

概括

化供体人乳 (PDHM) 对于早产婴儿在解后长达48小时仍然是安全的. 这项研究发现没有显著的营养或微生物学变化,这表明长期使用可以减少牛奶银行浪费.

科学领域:

人类牛奶银行
新生儿营养新生儿营养
微生物学微生物学

背景情况:

日本的指导方针在解后24小时丢弃巴氏化供体母乳 (PDHM).
以前的研究表明PDHM安全性长达48小时.
扩大PDHM的使用可以最大限度地减少浪费.

研究的目的:

评估冷藏PDHM在解后长达48小时的微生物安全性.
评估营养和免疫性质的保存.
通知可能修订的牛奶银行指南.

主要方法:

配对样本实验研究设计.
在冷解后24小时和48小时对PDHM的分析.
微生物培养,营养素分析 (巨量营养素,微量营养素) 和免疫物质测量 (sIgA,乳酸).

主要成果:

在PDHM中没有检测到24或48小时的细菌生长.
脂肪,碳水化合物,,,sIgA和乳糖的轻微,临床上没有意义的变化.
稳定的蛋白质和水平;观察到轻微的pH值增加.

结论:

冷藏的PDHM在解后48小时内保持微生物和营养完整性.
轻微的生化变异对于早产婴儿的药用没有临床意义.
支持将PDHM使用时间延长至48小时,可能会修订当前的指导方针.

关键词:

乳酸铁素是乳酸铁素的一种.这里是SIGA SigA.母乳养哺乳期母乳养捐赠者母乳是人类的母乳.过期数据过期数据冰箱冷藏机的冷藏机是什么意思

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