菌病对美国慢性病负担的贡献
Ria R Ghai1, Kaitlin Benedict1, Tom M Chiller1
1Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Clinical microbiology reviews
|March 5, 2026
概括
真菌感染可能会导致慢性疾病,这种联系比相反的研究少. 本综述探讨了真菌和抗真菌治疗如何影响慢性疾病的发展,敦促进行更多的研究.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 慢性疾病流行病学 慢性疾病流行病学
背景情况:
- 慢性疾病是美国的主要公共卫生挑战.
- 在全球范围内,真菌感染正在增加,其严重程度和抗真菌耐药性正在增加.
- 虽然慢性疾病增加了真菌感染的风险,但真菌对慢性疾病的影响不太清楚.
研究的目的:
- 审查有关导致慢性疾病发展的真菌感染的文献.
- 讨论将真菌感染与慢性疾病联系在一起的病理生理机制.
- 研究抗真菌疗法在慢性疾病病因学中的作用.
主要方法:
- 目前研究的文献综述.
- 对病理生理机制的分析.
- 检查真菌感染的直接影响,后果和治疗毒性.
主要成果:
- 真菌感染可以直接导致或加剧慢性疾病.
- 菌感染的后果会导致慢性疾病.
- 抗真菌疗法的毒性作用也可能导致慢性疾病状态.
结论:
- 真菌感染在慢性疾病的负担中起着重要的,未被认可的作用.
- 进一步的研究,监测,意识,诊断和治疗是至关重要的.
- 了解这种双向关系对于公共卫生至关重要.
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