紧急性数值评级尺度的验证以及与性结肠炎内镜,组织学和人测活动的相关性
Andreia Guimarães1, Ana Célia Caetano1,2, Inês Barbosa2
1Gastrenterology Department, Braga Local Health Unit.
European journal of gastroenterology & hepatology
|March 5, 2026
概括
葡萄牙紧急数字评分表 (U-NRS) 有效地测量了性结肠炎患者的肠急性. 这种经过验证的工具在临床实践中很容易用于评估这种常见症状.
科学领域:
- 胃肠病学 胃肠病学
- 临床评估工具 临床评估工具
- 炎症性肠道疾病 炎症性肠病
背景情况:
- 肠急性是性结肠炎 (UC) 中常见的,往往被低估的症状.
- 紧急数值评级表 (U-NRS) 是评估肠急症严重程度的工具.
- 翻译和验证葡萄牙语的U-NRS对于其在葡萄牙语人口中的临床应用至关重要.
研究的目的:
- 将U-NRS翻译成葡萄牙语,并将其验证为UC患者的临床使用.
- 为了确定UC队列中肠急症的流行率.
- 探索在缓解期患者的肠急性和临床,内镜,组织学和人测参数之间的关系.
主要方法:
- 该U-NRS被翻译成葡萄牙语,并在多个时间点 (T0,T1,T2) 给UC患者.
- 收集了患者报告的结果,包括PRO-2-UC,EQ-5D,EQ-VAS,IBD-Disk和全球感知效应量表.
- 评估了可接受性,可靠性,构造有效性,响应性和可解释性. 一个子组接受了西格莫显微镜和直肠测量.
主要成果:
- 在126名UC患者中,49.21%的人报告肠道急迫.
- 观察到测试重复测试的可靠性非常好 (ICC:0.768).
- 该U-NRS证明了与PRO-2-UC,IBD-Disk,EQ-VAS和EQ-5D的显著相关性,证实了构造的有效性. 发现U-NRS和直肠测量结果之间存在相关性.
结论:
- 葡萄牙语版的U-NRS是一个可靠和有效的工具,用于评估性结肠炎的肠急性.
- U-NRS是一个易于使用的仪器,适合整合到常规的临床实践中.
- 该研究强调了肠急症的普遍性及其与UC生理学参数的潜在联系.
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