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Updated: Mar 6, 2026

Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models
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线粒体PDHA1乙化调节乳酸依赖的表观遗传重编程,通过NUAK2促进纤维化

Yujie Wang1,2,3, Guanglian Du1, Jinjin Zhang1,3

  • 1Department of Respiratory and Critical Care Medicine, Binzhou Medical University Hospital, Binzhou Medical University, Binzhou, 256603, China.

Cellular and molecular life sciences : CMLS
|March 5, 2026
PubMed
概括

一条新的途径将线粒体功能障碍与肺纤维化联系起来. 抑制pyruvate脱酶E1α亚单元 (PDHA1) 乙化和NUAK2可能为异常性肺纤维化 (IPF) 提供新的治疗方法.

关键词:
乙化 乙化是一种异形性肺纤维化症 异形性肺纤维化症乳化 乳化 乳化在 NUAK2 的时候,它是 NUAK2 .这就是PDHA1的原因.这是一个超级增强器.

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