相关实验视频

Updated: Mar 6, 2026

Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography

Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography

Published on: November 8, 2024

骨肌肉的体积和密度是否会影响患有狂宫肌肉瘤的儿科患者的生存结果?

Rida Salman¹, Esther Ngan², Zbigniew A Starosolski²

¹Department of Radiology, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.

La Radiologia medica

|March 5, 2026

概括

在CT扫描中,骨肌肉的特征会影响儿科狂肌肉瘤的结果. 较高的肌肉密度可能会提高生存率,而肌肉体积与性别相互作用以影响结果,强调需要营养支持.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
儿科儿科儿科

背景情况:

儿科拉布多米索尔科马是一种显著的儿童癌症.
身体组成,特别是骨肌肉,可能会影响治疗结果.
诊断CT扫描提供了关于肌肉特征的见解.

研究的目的:

调查诊断CT扫描中的骨肌肉特征与儿科狂肌肉瘤患者的临床结果之间的关联.
识别潜在的成像生物标志物来预测预后.

主要方法:

对118名儿科rhabdomyosarcoma患者的回顾性分析.
在诊断CT扫描上评估骨肌肉特征 (体积,密度).
单变量和考克斯回归分析,以评估与无事件和整体存活率的关系.

主要成果:

高龄和较高的肌肉量与事件和死亡率的风险增加有关.
年龄是无事件生存的重要预测因素.
较高的肌肉密度与改善的整体存活率相关.
肌肉体积和性别之间的显著相互作用影响了整体生存率 (男性更糟,女性可能更好).

结论:

在CT扫描中,骨肌肉的特征与儿科rhabdomyosarcoma的结果有关.
按性别调节的肌肉密度和体积可以作为预后指标.
在化疗期间通过营养和体力活动维持肌肉质量至关重要,因此需要进一步研究.

关键词:

身体组成身体组成肌肉体积大量肌肉体积肌肉密度肌肉密度肌肉密度拉布多米索尔科马 (Rhabdomyosarcoma) 是一种癌症.萨尔科佩尼亚是什么意思萨尔科佩尼亚

更多相关视频

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue

Published on: November 27, 2017

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

相关概念视频

Satellite Stem Cells and Muscular Dystrophy

Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...

Disorders of the Skeletal Muscle

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...