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Updated: Mar 6, 2026

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阿尔茨海默病中的PAR-1:病理生理学见解和机械学视角

Neha1, Snehashis Mandal2, Vipual Sharma2

  • 1Department of Pharmacy Practice, ISF College of Pharmacy, Moga, 142001, India.

Current medical science
|March 5, 2026
PubMed
概括

蛋白酶激活受体-1 (PAR-1) 在阿尔茨海默病 (AD) 中具有双重作用,加剧病理,同时也提供神经保护. 抑制PAR-1在阿尔茨海默病的临床前模型中显示出治疗潜力.

关键词:
粉样蛋白-β 是一种蛋白质.神经炎症是一种神经炎症.陶氏病理学是一种病理学.阿尔茨海默病 阿尔茨海默病星球细胞是星球细胞.血液-大脑屏障是什么?神经退行发生神经退行.蛋白酶激活受体-1 (PAR-1) 是一种蛋白质酶激活受体.突触性可塑性 突触性可塑性

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