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Updated: Mar 6, 2026

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

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在罕见和耐火癌症中基因组治疗匹配

Frank P Lin1,2,3, Subotheni Thavaneswaran1,2,3,4, John P Grady2,3

  • 1NHMRC Clinical Trials Centre, University of Sydney, Camperdown, New South Wales, Australia.

JAMA oncology
|March 5, 2026
PubMed
概括

将疗法与基因组生物标志物相匹配,可以改善晚期固体瘤的存活率,但只有在有前性临床试验证据支持的情况下. 这凸显了基于证据的框架对于精密瘤治疗的重要性.

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