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Updated: Mar 7, 2026

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缺乏ERG的内皮将IL8-CXCR2轴确定为解决中性肺血管损伤的治疗点

Vigneshwaran Vellingiri1, Vijay Avin Balaji Ragunathrao1, Jagdish Chandra Joshi1

  • 1Department of Pharmacology and Regenerative Medicine, University of Illinois Chicago, College of Medicine, Chicago, United States of America.

JCI insight
|March 5, 2026
PubMed
概括

缺少Erg的内皮细胞会通过减少关键蛋白A20来触发中性粒细胞过度活化和组织损伤. 恢复A20或阻断CXCR2可以防止急性肺损伤.

关键词:
内皮细胞是内皮细胞.炎症 炎症是一种炎症.这是天生的免疫力.肺部病理学 肺部病理学血管生物学 血管生物学

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