EpCAM 沉默抑制了侵略性的表型,并诱导了甲状腺癌细胞的部分再分化

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Updated: Mar 7, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Published on: February 3, 2023

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Teruo Nakamura1, Tomohiro Shibata1, Ken-Ichi Ito1

  • 1Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine, Asahi, Matsumoto, Japan.

PloS one
|March 5, 2026
PubMed
概括

皮质细胞粘附分子 (EpCAM) 通过促进脱差和转移,驱动激进的厌塑性甲状腺癌 (ATC). 抑制EpCAM可能为这种罕见的癌症提供一种新的治疗策略.

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