诊断前的经济困难:对晚期癌症呈现的影响以及查的作用
Sara Khor1,2, Kaiyue Yu3, Catherine R Fedorenko4
1The Comparative Health Outcomes, Policy, and Economics Institute, University of Washington, Seattle, WA.
概括
财务困难 (FH) 与晚期的癌症诊断有关,特别是在查的癌症中. 由于经济困难,缺乏查显著增加了晚期乳腺癌的风险.
科学领域:
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
- 健康的社会决定因素
背景情况:
- 经济困难 (FH) 是健康的重要社会决定因素.
- 预诊断FH对癌症在诊断阶段的影响需要进一步调查.
- 了解癌症查在调解这种关系中的作用至关重要.
研究的目的:
- 调查诊断前经济困难 (FH) 与癌症在诊断时的阶段之间的关联.
- 检查癌症查在FH和乳腺癌阶段之间的关系中的调解作用.
- 为了确定特定的癌症类型和查方式最受FH影响.
主要方法:
- 一项使用链接SEER注册表,信用报告和医疗保健索赔数据 (2014-2017年) 的病例控制研究.
- 根据信用报告指标定义的财务困难,发生在诊断前两年内.
- 使用多变量逻辑双项回归和中介分析来评估关联和中介效应.
主要成果:
- 在50,148名癌症患者中,有30%患有FH,与14%的晚期诊断概率增加有关.
- 在有组织查 (aRR 1.25) 和体检 (aRR 1.44) 的癌症中,FH和晚期诊断之间的关联更为强烈.
- 在乳腺癌患者中,70%的晚期诊断风险增加归因于未接受查.
结论:
- 诊断前的经济困难是影响癌症诊断阶段的重要因素.
- 缺乏癌症查,特别是乳腺癌,在很大程度上解释了FH和晚期诊断之间的联系.
- 调查结果强调,需要采取干预措施,改善面临经济困难的个人对查的准入.
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