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Updated: Mar 7, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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在低催化剂负载下对螺旋活性和螺旋活性进行酶选择合成

Takeru Saito1, Antonio Navarro2, Huw M L Davies1

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|March 5, 2026
PubMed
概括

这项研究介绍了一种高效的催化方法,用于从二乳和乳中合成螺旋cyclopropanes. 催化过程实现了优异的产量和立体选择性,即使催化剂负载极低.

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