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结核性硬化综合体早期声乐发育预测语言,但不是自闭症结果

Tanjala T Gipson1, Edina R Bene2, Ching-Chi Yang3

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此摘要是机器生成的。

结核性硬化综合体 (TSC) 的早期语言障碍可以使用婴儿的正规语比率 (CBR) 预测. 这种语音测量可能有助于更早地识别TSC儿童的语言困难.

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自闭症 自闭症 自闭症圣经中的语是正统的.早期的言语和语言.婴儿的发声是婴儿的发声.结核性硬化综合体 结核性硬化综合体可挥发性 可挥发性

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科学领域:

  • 儿科神经学 儿科神经学
  • 发育儿科 发育儿科
  • 语音和语言病理学

背景情况:

  • 语言障碍影响大部分结核性硬化综合体 (TSC) 患者,往往导致评估延迟.
  • 婴儿的声乐行为,特别是规范的喋喋不休比率 (CBR) 和发言能力,是早期语言发展的关键指标.
  • 以前的研究表明,TSC婴儿的CBR和可变性较低,需要进一步调查.

研究的目的:

  • 为了进一步描述TSC.婴儿的正规喋喋不休比率 (CBR) 和发言能力.
  • 评估CBR和可言性对自闭症谱系障碍 (ASD) 和TSC语言结果的预测能力.
  • 确定CBR的预测贡献是否独立于其他已知的语言预测器.

主要方法:

  • 分析了202个12个月龄的婴儿记录,这些记录来自TSC患者.
  • 利用线性回归来预测基于语音测量的语言结果.
  • 采用逐步多重回归和后勤回归来评估语言和ASD的预测能力,分别.

主要成果:

  • 与典型发育的婴儿相比,患有TSC的婴儿表现出较低的CBR和可变性.
  • 在患有TSC的婴儿中,CBR显著预测了24个月的语言结果,超过了其他已知的预测因素.
  • 在这个队列中,CBR和可言性都没有表现出对自闭症谱系障碍 (ASD) 的预测能力.

结论:

  • 规范喋喋不休的比率 (CBR) 显示了作为一种有价值的工具的潜力,用于早期识别患有TSC的婴儿语言障碍.
  • 早期的声乐评估可能有助于及时干预这一群体的语言发展.