纤维肌痛和更年期:有好处的朋友?
Arriana Gkouvi1, Katerina-Maria Kontouli2, Eleni C Pardali1
1Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, Larissa University Hospital, University of Thessaly, Biopolis, Larissa, Greece.
Maturitas
|March 5, 2026
概括
纤维肌痛症状在绝经期间恶化,影响生活质量. 更高的体重指数 (BMI) 与纤维肌痛和更年期症状严重程度的增加有关.
科学领域:
- 妇女健康 妇女健康
- 类风湿病学 类风湿病学
- 绝经研究 绝经研究
背景情况:
- 纤维肌痛和更年期共享重叠的症状,如疼痛和疲劳.
- 更年期过渡可以加剧纤维肌痛症状,增加患者负担.
研究的目的:
- 为了检查纤维肌痛和更年期之间的关系.
- 为了确定纤维肌痛影响增加和更年期症状严重性的预测因素.
主要方法:
- 169名纤维肌痛患者完成了修订的纤维肌痛影响问卷 (FIQR) 和格林高潮标尺 (GCS).
- 记录了社会人口统计数据,药物使用和更年期状态.
- 线性回归分析确定了症状严重程度的预测因素.
主要成果:
- 更糟糕的纤维肌痛 (更高的FIQR分数) 预测更严重的绝经症状 (β=0.38,p<0.001).
- 更高的BMI与更高的更年期症状严重程度相关 (β=0.84,p=0.001) 和纤维肌痛影响 (β=1.1,p<0.001).
- 纤维肌痛在51%的患者中发生在更年期之前,并在21.9%的患者中同时发生.
结论:
- 纤维肌痛和更年期症状显著重叠,加剧了整体症状负担.
- 较高的BMI与更年期纤维肌痛患者的疾病影响更大,生活质量更差有关.
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