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Updated: Mar 7, 2026

A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer
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在癌症治疗中准ATR:一种药物发现视角

Yue Lai1, Wenzhe Zhao1, Yan Wang1

  • 1Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.

Bioorganic chemistry
|March 5, 2026
PubMed
概括

ATAXIA telangiectasia和Rad3相关的 (ATR) 激酶对于DNA损伤反应和癌细胞生存至关重要. ATR抑制剂是有希望的治疗点,正在研究下一代药物和组合策略.

关键词:
在ATR降解器中,降解器是ATR降解器.作为ATR抑制剂的使用者.在ATR激酶中,有ATR激酶.对DNA损伤的反应反应癌症治疗疗法 癌症治疗结合策略 结合策略发现药物的发现.

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