Kaiyuan Zhu1, Wan-Chen Li1, Jamin Liu2

  • 1Department of Pharmacology and Cecil H. and Ida Green Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA; Altos Labs, Redwood City, CA, USA.

Molecular cell
|March 5, 2026
PubMed
概括

研究人员发现了IncPRESS1,这是一种调节细胞命运的双功能RNA. 它作为核中的长非编码RNA (lncRNA) 和细胞质中的微蛋白,协调发育.

相关概念视频

Lineage Commitment01:21

Lineage Commitment

Commitment is the  process whereby stem cells:
4.5K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
7.5K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

2.7K
Coordination of Gene Expression Processes in Bacteria01:29

Coordination of Gene Expression Processes in Bacteria

The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
785
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
12.0K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

4.2K