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胰腺二次瘤的胰腺切除后的结果:一个单一中心的经验
Claire L Stevens1, Wing Joe Chim2, Oliver Pickering3
1Hepatopancreatic Biliary Surgery Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Surgery, University Hospital Geelong, Geelong, Australia.
概括
来自非胰腺,非神经内分泌瘤的孤立转移性疾病的胰腺转移切除可以实现良好的长期生存. 谨慎的患者选择和大量的手术中心是最大限度地减少风险和最大限度地提高结果的关键.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 从非胰腺,非神经内分泌恶性瘤中分离的胰腺转移是罕见的.
- 对转移性疾病的胰腺切除很少进行.
- 了解症状和结果对于患者管理至关重要.
研究的目的:
- 在转移性疾病的情况下评估胰腺切除的指示.
- 评估胰腺切除对于非胰腺,非神经内分泌瘤的结果.
- 为了分析胰腺转移切除术后的生存率和复发率.
主要方法:
- 预期管理数据库的回顾性分析.
- 包括因转移性疾病而接受胰腺切除的患者.
- 收集有关人口统计,操作结果,生存率和复发率的数据.
主要成果:
- 在844例胰腺切除 (3.3%) 中,26名患者符合纳入标准.
- 最常见的原发性瘤是细胞癌,黑色素瘤,乳腺癌和结直肠癌.
- 平均总生存时间为41个月;平均无病生存时间为17个月. 术后发病率为42.9%,没有死亡.
结论:
- 胰腺转移切除可以提供良好的长期生存.
- 低发病率和死亡率可以在高人数的中心实现,并经过仔细的患者选择.
- 这种方法是选择胰腺转移性疾病患者的可行选择.
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