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Updated: May 5, 2026

Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells
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Published on: October 1, 2010

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导致双重葡萄糖失调的SUR1突变的分子和功能特征

Davoud Amirkashani1, P V Migisha Ntwali2, Behnoosh Tasharrofi3

  • 1Division of Endocrinology and Metabolism, Ali-Asghar Children Hospital, Iran University of Medical Sciences, Tehran, 1449614535, Iran.

International journal of biological macromolecules
|March 5, 2026
PubMed
概括

研究人员在糖尿病患者中研究了SUR1 Y123F变体,发现它改变了对ATP敏感的通道活性. 这可能解释高血糖症,但需要进一步的研究来了解低血糖症.

关键词:
计算生物学是一种计算生物学.糖尿病 糖尿病 糖尿病葡萄糖调节失调的情况K ((ATP) 是一个ATP系统.突变突变是一种突变.在SUR1中使用.

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