结构对齐器在功能域注释中的比较性能

Poorya Mirzavand Borujeni1, Reza Salavati2

  • 1Institute of Parasitology, McGill University, Canada.

PubMed
概括

使用AlphaFold模型的基于结构的蛋白质域注释显示出希望,Reseek在灵敏度方面表现出色. 然而,像HMMER这样的序列配置文件方法对于家族级别的注释仍然优越,特别是当包含配置文件信息时.

相关概念视频

Structural Classification of Joints01:20

Structural Classification of Joints

Joints, also known as articulations, are classified based on their structural characteristics, i.e., based on whether the articulating surfaces of the adjacent bones are directly connected by fibrous connective tissue or cartilage, or whether the articulating surfaces contact each other within a fluid-filled joint cavity. These differences serve to divide the joints of the body into three structural classifications.
A fibrous joint is where the adjacent bones are united by fibrous connective...
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Functional Classification of Joints01:09

Functional Classification of Joints

Functional Classification of Joints
The functional classification of joints is determined by the amount of mobility between the adjacent bones. Joints are functionally classified as a synarthrosis or immobile joint, an amphiarthrosis or slightly moveable joint, or as a diarthrosis, a freely moveable joint. Fibrous and cartilaginous joints can be functionally classified as either synarthroses  or amphiarthroses, whereas all synovial joints are classified as diarthroses.
Synarthrosis
An...
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