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Updated: Mar 7, 2026

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques
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通过动态冷聚合试验和质谱法研究耐热的冷蛋白

Jing Jing Wang1, Chiang Lu2, Enny Soesilowati3

  • 1Department of Immunology, Flinders University & SA Pathology, Bedford Park, SA, Australia.

Clinica chimica acta; international journal of clinical chemistry
|March 5, 2026
PubMed
概括

这项研究报告了一名患有型肝炎的患者罕见的耐热结晶球蛋白.对此类病例的认识对于准确检测结晶球蛋白和避免诊断实验室错误负面结果至关重要.

关键词:
自动抗体是一种自身抗体.结晶球蛋白是什么 结晶球蛋白是什么质谱测量质量谱测量

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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